Advances in Radiation Oncology in Lung Cancer by Dusan Milanovic (auth.), Branislav Jeremic (eds.) PDF

By Dusan Milanovic (auth.), Branislav Jeremic (eds.)

ISBN-10: 3642199240

ISBN-13: 9783642199240

Although many years of laboratory and scientific learn have ended in incremental development in therapy end result, lung melanoma continues to be some of the most lethal illnesses. within the moment, thoroughly up to date version of this finished e-book, the various world’s major lung melanoma experts speak about the new advances within the radiation oncology of lung melanoma and think about the most recent examine findings. the 1st 3 sections disguise the elemental technology of lung melanoma, medical investigations, together with histology and staging, and a variety of basic remedy issues. present therapy techniques for nonsmall phone and small telephone lung melanoma are then defined and evaluated intimately, with due awareness to novel methods that promise additional advancements in end result. some of the kinds of treatment-related toxicity are mentioned, and caliber of existence reports and prognostic elements also are thought of. After comparing the most recent technological and organic advances, together with IMRT, IMAT, cyber knife remedy, and tomotherapy, the ebook concludes by way of thorough attention of particular facets of medical study in lung melanoma.

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Extra resources for Advances in Radiation Oncology in Lung Cancer

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Nature 473:101–104 Wistuba I, Behrens C, Virmani AK et al (2000) High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 60:1949–1960 Wolff H, Saukkonen K, Anttila S et al (1998) Expression of cyclooxygenase-2 in human lung carcinoma. Cancer Res 58:4997–5001 Wong DW, Leung EL, So KK et al (2009) The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS.

2006). A similar association between VEGF expression and poor prognosis also was reported in SCLC (Ohta et al. 1996; Salven et al. 1998). In addition to determining tissue and tumor VEGF protein and mRNA expression, it is also possible to measure VEGF concentrations in body fluids. When this was done in lung cancer patients, serum or plasma VEGF levels were observed to increase with tumor stage progression (Takigawa et al. 1998; Matsuyama et al. 2000; Tamura et al. 2002). Also, patients with elevated serum or plasma VEGF levels at diagnosis had a poorer response to therapy and worse survival (Salven et al.

J Virol 42:773–779 Voortman J, Lee JH, Killian JK et al (2010) Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors. Proc Natl Acad Sci U S A 107(29):13040–13045 Wagner PL, Stiedl AC, Wilbertz T et al (2011) Frequency and clinicopathologic correlates of KRAS amplification in nonsmall cell lung carcinoma. Lung Cancer (Epub ahead of print: 7 Apr, 2011) Weir BA, Woo MS, Getz G et al (2007) Characterizing the cancer genome in lung adenocarcinoma.

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Advances in Radiation Oncology in Lung Cancer by Dusan Milanovic (auth.), Branislav Jeremic (eds.)


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